Tooth pain at night is usually caused by acute pulpitis, it is recommended that painkillers to relieve, such as ibuprofen, acetaminophen and other drugs, the pain can not be relieved when the timely medical treatment for pulp drainage. 1. The main symptoms of acute pulpitis are night pain, spontaneous pain, pain can not be localized and pain is often radiating, temperature stimulation will aggravate the pain. When the symptoms of pulpitis are obvious and cannot be treated, oral painkillers can be taken to relieve the pain, such as ibuprofen, acetaminophen and other drugs to temporarily relieve pain. 2. Drug allergy is prohibited, should pay attention to diet during the use of drugs, do not drink alcohol. Acute pulpitis acute attack using drugs is ineffective, can only temporarily relieve the pain, should also be opened in time to drain the pulp, and then carry out perfect root canal treatment. Acute pulpitis is usually caused by a tooth defect that leads to infection of the pulp tissue. After perfect root canal treatment, restorative treatment should also be done, because the tooth after root canal treatment is easy to be split under external force, so restorative treatment should be done to protect the affected tooth, such as inlay restoration, crown restoration, and the use of medication should be in accordance with the doctor’s instructions.