The use of long-acting antihypertensive drugs, which can be taken orally once a day to smoothly control blood pressure for 24 hours, is in line with modern antihypertensive concepts. Antihypertensive drugs are divided into several categories according to their mechanism of action, which are described below. I. Long-acting calcium antagonists. These include amlodipine, felodipine, and nifedipine controlled-release tablets. Second, long-acting beta-blockers. Reduce blood pressure by reducing sympathetic excitation, reduce myocardial contractility, including bisoprolol, metoprolol succinate. Diuretic drugs. Reduce blood pressure by reducing excess water in the body, including indapamide tablets. Fourth, ACEI or ARB class. Lower blood pressure by reducing renin and aldosterone levels, dilating blood vessels and many other effects, including enalapril, benazepril, ramipril, telmisartan, irbesartan, etc. Long-acting antihypertensive drugs are usually chosen as one alone or a combination of 2-3 different types in small doses, usually taken orally once daily, immediately upon waking up in the early morning.