Occupational lesions of the spinal cord refer to tumors within the spinal cord, which are called occupational lesions because they can compress the spinal cord and take up space in the spinal cord. There are many causes of spinal cord compression, including tumors originating from the spinal cord itself, such as nerve sheath tumors, spinal cord gliomas, ventricular meningiomas, malignant metastatic tumors originating from the spinal column or other organs, and leukemia, which account for more than one-third of the cases of spinal cord compression diseases. Thus, those with leukemia can cause spinal cord compression disorders to some extent, as leukemia is a neoplastic lesion of the blood system and one of the causative factors of spinal cord occupying lesions. After the leukemia continues to aggravate some patients will have spinal cord compression symptoms or develop intramedullary leukemia infiltration. It is very common for patients with acute leukemia to present with spinal cord space as the first manifestation of leukemia, and once diagnosed, they should receive standardized treatment under the guidance of a physician.