The difference between ligament ossification and calcification is the degree of difference; ossification is excessive calcification. Ligament calcification is the result of ligament injury due to a variety of reasons, such as joint degeneration, trauma, inflammatory stimuli, etc. Calcium phosphate salts and carbonates are deposited in the ligaments, which finally lead to ligament calcification. Ligament calcification is mainly manifested as activity limitation, and some patients may have localized redness and swelling and other symptoms. In the chronic phase of ligament calcification, there is usually only localized soreness and mild limitation of joint movement. In the acute stage, patients will experience increased pain and significant limitation of movement. When ligament calcification further develops, local calcium salt deposition increases and gradually progresses to ossification, i.e., the degree of calcification increases. The patient’s shoulder joint activities are severely limited, and there is obvious pressure pain in the affected area. When ligament calcification or ossification occurs, it is recommended to go to the hospital in time for targeted treatment or therapy.