Ultra-picosecond spot removal generally refers to ultra-picosecond laser spot removal with exact clinical effect, which is generally carried out for 3~5 times to achieve the ideal effect. Ultra-picosecond laser spot removal is generally carried out for 3~5 times before the effect is achieved, specifically related to the patient’s type of pigmentation, severity of pigmentation and daily care and other factors, and cannot be generalized. Ultra-picosecond laser spot removal is a kind of laser technology, that is, the pulse duration (pulse width) emitted by each beam of laser reaches the level of picoseconds, so that the skin pigment particles are exposed to the highly concentrated energy, and the pigment particles will be broken down more precisely and the pigment absorption will be accelerated through cellular metabolism to lighten the pigment spots. It is recommended that patients choose professional and regular medical institutions to do picosecond laser spot removal, and follow the doctor’s instructions to take good care of them to reduce the occurrence of adverse reactions.