Diabetic gangrene occurs mostly in middle-aged and elderly people; more men than women, with a male to female ratio of 3:2; the average duration of diabetes mellitus is about 10 years, and gangrene is common in the lower extremities, accounting for 92.5%, and rare in the upper extremities, accounting for about 7.5%; unilateral onset accounts for about 80%, and bilateral onset accounts for about 20%; simultaneous gangrene of the toes and soles is common, accounting for 77.5%; simultaneous gangrene of the toes and lower legs accounts for 5%, and gangrene of the lower legs only accounts for 5 percent; toe or finger onset accounted for 12.5 percent. Diabetic patients with gangrene will be induced diabetic foot, diabetic foot we have heard that the danger is very serious, it will not only affect the life and work of diabetic patients, but also lead to amputation and even death, so do not underestimate the gangrene of the extremities, to timely prevention of gangrene of the extremities. Diabetic gangrene is a common symptom of diabetic foot, if not well controlled may be amputated, or even life-threatening, so the prevention of diabetic gangrene requires attention: 1, active treatment of diabetes, strict control of hyperglycemia. 2, strict control of hyperlipidemia. Eat less food with high cholesterol and high fat content. 3, active treatment of hypertension. 4, adhere to daily exercise, maintain normal weight, obese people try to reduce weight. 5, absolutely prohibit smoking. 6.If there is blood vessel obstruction, try to get rid of it. 7.Educate the patient and promote knowledge of foot care. 8, daily inspection of the foot, if found blisters, skin cracks, abrasions, corns, calluses, tinea pedis, nail gouges, etc. should be promptly treated and treatment. 9, maintain foot hygiene, wash feet as important as washing the face, wash feet every night with warm water (not more than 40 ℃) and soft soap, dry the toes with a soft absorbent towel, coated with lanolin or vegetable oil. 10, shoes should be wide, comfortable, fit the foot, so that the toes in the shoes completely straight, and slightly movable, the shoes should be breathable, to leather shoes cloth shoes is good; advocate wearing cotton socks, socks should be soft, fit the foot, the tip of the socks should not be too tight, do not wear elastic mouth socks, do not wear socks with holes or repair uneven. Those who sweat a lot should put a little talcum powder in their shoes and socks, and socks should be changed and washed regularly. 11. Avoid damage to the skin of the extremity, which can lead to severe gangrene even if slightly damaged. Shoes and socks should not be too small or too tight, do not wash your feet in water that is too hot, do not walk barefoot, do not wear shoes barefoot, do not put on skin damaging tape, do not use strong disinfectants such as iodine, carbolic acid, etc. Toenail cutting should not be cut too short, but flush with the toes. 12, gently massage the foot and calf can improve local blood circulation.