Bone pain in the middle of chest may be caused by sternum injury, tumor metastasis, heart disease and other factors. 1. Sternum injury: when the patient’s chest suffers a heavy blow, it may lead to sternum fracture or acute soft tissue injury, in which the patient’s sternum will produce more intense pain, and may be accompanied by the symptom of activity limitation. 2. Tumor metastasis: Tumor metastasis may also lead to chest bone pain, such as esophageal cancer, mediastinal tumor and so on. In this case, besides pain, patients usually have symptoms such as weight loss and mental fatigue. 3. Heart disease: some heart diseases, such as coronary heart disease, myocardial infarction, etc., may also produce chest pressure pain. There are many reasons for the pain in the middle of the chest bone, we suggest that patients go to the hospital in time for examination, to clarify the cause of the disease, and then further treatment.