The weakness of the whole body when both legs are exerted after lumbar spine minimally invasive surgery may be the result of incomplete recovery, muscle atrophy, and so on. 1. Not fully recovered: lumbar disc herniation mainly compresses the nerves, which will cause a series of symptoms. After the surgery, the compressed nerves are not fully recovered, and weakness of both legs will occur in this case. In addition, there are some surgeries that need to pull and stimulate the dural sac and nerve roots during the surgery, which will also cause weakness of both legs, and the symptoms will usually be relieved after a period of time. 2. Muscle atrophy: after minimally invasive lumbar spine surgery, you need to stay in bed for a period of time, if you don’t carry out functional exercise at this time, muscle atrophy will occur, and when you get out of bed, you will also have weakness of legs and general weakness, which can be relieved through appropriate exercise. After lumbar spine minimally invasive surgery, weakness of legs and generalized weakness should be treated symptomatically according to the cause of the disease, and it is recommended that after lumbar spine minimally invasive surgery, appropriate functional exercise.