Alteplase is a thrombolytic drug, its main component is glycoprotein, it plays a pharmacological role is mainly through the lysine residues and fibrin binding, and activates the fibrin-binding fibrinogen into fibrinolytic enzyme, into fibrinolytic enzyme this situation can play a certain role in thrombolysis, its indications are mainly for acute myocardial infarction thrombolysis, acute ischemic stroke, deep vein thrombosis It has some effect on the formation of such cases. In addition, alteplase is also used for thrombolysis of pulmonary embolism, but it has the risk of bleeding, so it has certain contraindications, such as recent serious internal bleeding, especially cerebral bleeding. Another contraindication is the presence of intracranial tumors, intracranial arteriovenous malformations or arteriovenous tumors. In addition, the presence of hematologic disorders, such as thrombocytopenia, is also inappropriate.