The inexplicable appearance of burning pain in the palm of the palm of many factors, you need to carefully observe the appearance of the painful areas of the palm. If the appearance does not have any change, the skin color is not abnormal, purely to burning, pain is mainly, consider is infected with chickenpox – herpes zoster virus caused by the limited parts of the tonic herpes zoster, neurological radiating pain need to choose to use oral vasiclovir hydrochloride tablets for treatment. If there are obvious erythema and papules in the palm area, it is considered to be caused by irritation and allergy, and it is recommended to use glycerine lotion or zinc oxide cream, and if necessary, it can be combined with oral vitamin B nutritional nerves, which can effectively alleviate the pain. If the palm area appears obvious layer peeling and dense pustules, consider palmoplantar pustulosis, related to genetic factors, it is recommended to choose to use clobetasol propionate cream, carbotriol ointment and so on.