Vitiligo can be cured in some patients, if the cause of the disease can be found (such as thyroid disease), the affected area is small after timely treatment, it can be cured. The treatment needs to be through standardized drug therapy, physical therapy, transplantation therapy and so on. Vitiligo treatment has some difficulties, the condition is easy to delay recurrence, a few vitiligo patients can be standardized treatment to achieve clinical cure. Vitiligo can be treated with topical medications, including glucocorticoid preparations such as betamethasone valerate, calcium-modulated phosphatase inhibitors such as tacrolimus ointment, vitamin D3 derivatives such as calcipotriol ointment. Oral glucocorticoids such as prednisone can also be administered. Physical therapy such as phototherapy NB-UVB and 308nm excimer laser can also be performed. Transplantation therapy is suitable for patients in the stable stage. Autologous epidermis or melanocytes can be transplanted into the depigmented area to achieve the purpose of color restoration. Combined with phototherapy can improve the efficacy. When vitiligo appears, go to the hospital in time for examination, and use the above drugs should follow the doctor’s instructions.