Parkinson’s disease develops to a certain period of time, the effect of drugs is not good, you need to consider the surgical treatment of the brain pacemaker, effective control of symptoms, so that patients can take care of their own life, live a better life. But the cost of surgery is not a little bit, many families do not dare to try to do to the patient, is afraid of surgery effect is not good, they are watching and also in the understanding, some patients and their families may also see some surgery effect is not good patients, and do not dare to do the surgery, then why these patients will surgery effect is not good? After carefully analyzing these cases of poor surgical results, the following factors are found to influence the surgical results of implanted brain pacemaker in Parkinson’s disease. 1, the diagnosis of Parkinson’s disease Surgical treatment of brain pacemaker is effective for primary Parkinson’s disease, but not for secondary Parkinson’s disease and Parkinson’s superimposed syndrome, and is generally not recommended, so it is very important to confirm the diagnosis of Parkinson’s disease before surgery. 2, preoperative examination Parkinson’s disease patients are mostly middle-aged and elderly people, most of them are between 50 and 75 years old, and many of them suffer from long-term cardiovascular and cerebrovascular diseases, and some of them are even accompanied by psychiatric symptoms. Therefore, detailed preoperative examination and psychiatric evaluation are needed to assess whether they are able to undergo surgery as well as the prognosis of the surgery. 3, the appropriate timing of surgery Many Parkinson’s disease patients and their families may know that Parkinson’s disease has surgical treatment, some may think that surgical treatment is the development of the disease is serious time to consider, in fact, this is not the case, there is a certain time for surgery, also known as the “window period”, that is, drug “honeymoon period”, after the medication has been taken, it is not necessary to take medication for the first time. After the “honeymoon period” of medication, the effect of medication is slow, the effective time is short, the effect of symptom improvement is not good, or the fluctuation of symptoms has occurred, this time should consider surgical treatment, rather than waiting for the seriousness of the disease, because the patient’s age, physical condition may also deteriorate, and may even lose the opportunity for surgery. Therefore, the effect of missing the timing of surgery may not be good. 4. Accurate electrode implantation Typical symptoms of Parkinson’s disease include tremor, stiffness, slow movement and abnormal posture and gait. The severity of each patient’s condition varies, with some patients experiencing obvious tremor and others experiencing obvious stiffness or slow movement. Therefore, the target point of surgery will also be different. After finding the target point suitable for the patient’s condition, the accurate implantation of electrodes is also very critical. All of this can affect the outcome of the surgery. It is recommended that patients consider the surgery, choose a large hospital, operating room and examination, advanced surgical instruments, and most importantly, surgery experienced Parkinson’s disease diagnosis and treatment experts and their team of doctors, so that in this link, can reduce the impact on the effect of the surgery. 5, postoperative program control Postoperative program control is also a very important part of the impact of the postoperative effect, program control is based on the specific symptoms of each patient and the adjustment of parameters, including voltage, frequency, pulse width and other values, constantly adjusted to achieve a suitable control state, experienced program control division can grasp the characteristics of the patient’s condition in a short period of time, and to give adjustments. 6, postoperative drug adjustment There are many patients who think that after surgery, there is no need to take medication, in fact, postoperative patients do not take medication is a very small number of patients, basically the patients have to take medication after surgery, postoperative medication can be reasonably used to enhance the therapeutic effect, but it can be reduced the amount of preoperative medication. Surgery is not a substitute for medication, but works synergistically with anti-Parkinson’s disease medications to improve efficacy.