Metformin, as a common medicine for many diabetic patients, has some misunderstandings in its daily use, and here’s how to properly understand it. Initially, people found “guanidine” with hypoglycemic effect from goat bean (a kind of pasture), and later refined through scientific processing to improve the efficacy and remove the toxicity, and finally turned into Metformin, which is widely used nowadays. Nowadays, research shows that Metformin can achieve the purpose of controlling blood sugar through the following mechanisms: 1. Metformin can increase the sensitivity of insulin, so that insulin’s ability to lower blood sugar becomes larger, thus achieving the effect of lowering blood sugar. 2. 2.Metformin has the effect of reducing the output of liver glycogen. 3.Metformin can increase the consumption of sugar by tissues and organs such as muscle and liver. Metformin is suitable for type 2 diabetes mellitus, especially for obese people, it can reduce both fasting and postprandial hyperglycemia and triacylglycerol without causing weight gain, and can be used in combination with other oral antidiabetic drugs and insulin. Adverse reactions that may occur during administration are: 1. Occasionally, nausea, vomiting, diarrhea, abdominal pain, abdominal distension, dyspepsia, fatigue and other digestive symptoms. 2, Occasionally fatigue, weight loss, headache, dizziness, abnormal taste, rash, chills, flu-like symptoms, palpitations, flushing. 3. Rarely, lactic acidosis is manifested by vomiting, abdominal pain, hyperventilation, and impaired consciousness. Some people think that it “harms the liver and kidneys”, in fact, this is wrong, normal liver and kidney function, taking a safe dose of metformin within the scope of the general will not cause liver function abnormalities or kidney function abnormalities. But when the liver and kidney function is incomplete, the use of metformin received restrictions or contraindications. As long as it is taken under the supervision of a doctor in a regular hospital, it is generally safe.