Chemotherapy is generally not very painful. Some patients may experience side effects, mainly nausea and vomiting, due to poor physical condition or discomfort with chemotherapy drugs, but they are generally tolerable. Because chemotherapy is a systemic treatment against cancer, there is no other treatment that can completely replace chemotherapy. In order to control the development of the disease and prolong the survival period, a little bit of pain must be endured. The preventive application of anti-emetic and anti-allergic drugs before chemotherapy can alleviate the side effects caused by chemotherapy, and patients may continue to cooperate with chemotherapy when they feel better. What patients should do themselves is to drink more water during chemotherapy and keep urine flowing, which helps the metabolism of chemotherapy drugs and can also reduce chemotherapy side effects.