The first is probably a common wart, which is mainly caused by infection with the human papilloma virus HPV. It is caused by a deep infection of the virus due to a small break in the skin surface. In terms of treatment, you can apply recombinant human interferon alpha 2b ointment together with retinoic acid ointment for treatment. The second type of acne is nodular acne, which is mainly due to endocrine disorders and local inflammation caused by Propionibacterium acnes infection. The purpose of the treatment is to cure the disease.