Generalized maculopapular rash may be caused by eczema, ringworm, contact dermatitis and other diseases, which can be treated by general treatment and medication. 1. Eczema: If eczema causes maculopapular rash all over the body, patients should stay away from disease-causing factors in daily life, and at the same time avoid scratching the affected area to avoid aggravation of the condition. Glucocorticoid drugs can be used externally as prescribed by the doctor, to play an anti-inflammatory, anti-allergic effect, common drugs are hydrocortisone, trimethoprim, etc., can be combined with oral antihistamines such as loratadine and other treatments. 2. Tinea corporis: generalized maculopapular rash may also be caused by tinea corporis, patients try to wear sweat-absorbent, breathable, soft clothing, need to pay attention to personal hygiene, diligent bathing. During the period you can follow the doctor’s instructions to use antifungal drugs, such as miconazole, ketoconazole cream, oral terbinafine and other drugs. 3. Contact dermatitis: contact dermatitis can also cause maculopapular rash all over the body, patients should avoid contact with allergic factors, wear loose clothing, avoid rubbing the affected area. Also follow the doctor’s instructions for external glucocorticosteroids, such as halometasone, mometasone furoate, etc., combined with antihistamine drugs such as loratadine and other treatments. There are many diseases that cause generalized maculopapular rash, it is recommended to go to a regular hospital to clarify the cause of the disease and cooperate with the doctor to standardize the treatment.