Thoracic twelve vertebrae fracture can be treated conservatively if the injury is mild and surgically if the injury is severe. Basic recovery can be achieved in 3 to 6 months after regular treatment. Thoracic vertebral fracture is mostly seen in middle-aged and elderly people with compression fracture, which can be treated conservatively if the fracture injury is mild. If the fracture is more serious, surgery can also be used, conservative treatment and surgical treatment can achieve good therapeutic effect, about 3~6 months will be able to achieve basic recovery. Conservative treatment is mainly symptomatic rest, to be strictly bedridden, oral celecoxib and other non-steroidal anti-inflammatory drugs for pain and other ways. Surgery can be used if the injury is severe and conservative treatment does not provide relief. Surgical treatments include minimally invasive percutaneous vertebroplasty and traditional incision and fixation. The above medications need to be used under doctor’s supervision, avoid self-medication.