The main reason for irregular menstruation is endocrine disorders, such as estrogen, follicle-stimulating hormone, luteinizing hormone abnormalities, especially testosterone may increase, resulting in acne and acne. In this case, western medicine can be regulated by short-acting oral contraceptives, which can reduce testosterone while regulating menstruation, thus reducing the symptoms of acne, such as Momoflurane or Daying-35, especially Daying-35 is effective in treating acne. Choosing topical medications such as retinoic acid and sulfur lotion can also alleviate the symptoms of acne, or taking oral Chinese medicinal preparations to regulate menstrual irregularities, thus adjusting the endocrine to alleviate acne.