The child high fever 41 degrees such as for the cranial brain outside of the infection such as pneumonia, etc. caused by the brain, then there is no obvious effect; such as for the intracranial infection caused by the brain may have a certain effect on the brain. Children with a high fever of 41 degrees Celsius, suggesting the presence of more serious infections, such as bacterial infections caused by pneumonia, mostly combined with other symptoms, such as fatigue, chest pain, coughing, irritability, etc., in a positive and reasonable is by the antibiotics more than the brain will not have an impact. If the intracranial infectious diseases, such as bacterial meningitis, can also make the child appear high fever temperature up to 41 ℃, the disease will have some effect on the brain. About 10% to 20% of survivors are left with various serious neurological sequelae. Common neurological sequelae include hearing loss, intellectual regression, recurrent convulsions, delayed language skills, visual impairment, and behavioral abnormalities. It is recommended that children with a high fever of 41 ℃ go to the hospital for standardized diagnosis and treatment in a timely manner to avoid delays.