Peeling and oozing of areola can be seen in breast eczema or eczema-like breast cancer. 1. Mammary eczema: it can be caused by living environment, mental stress, etc. The most common location is the nipple and areola, and the manifestations of acute mammary eczema include pimples, peeling skin and oozing. The main treatments include general treatment, such as removing the cause of irritation, avoiding scratching, etc., and medication such as tacrolimus ointment as prescribed by doctor. 2. Eczema-like breast cancer: its pathogenesis is very similar to that of breast eczema, and it is a kind of breast cancer with lower malignant degree, whose main manifestations include redness, itching, oozing and peeling of nipple. The main treatment method is surgery, supplemented by radiation therapy and chemotherapy. Peeling and oozing of the areola should be treated promptly by a doctor. The use of medication should be under the guidance of a doctor.