Stone attack can take non-steroidal anti-inflammatory analgesic drugs, such as ibuprofen, diclofenac sodium, and in severe cases, drugs such as tramadol hydrochloride can be taken for pain relief. Most of the pain caused by stone attack is due to the change of stone location, thus stimulating the local mucosal nerves caused by pain. 1. Non-steroidal anti-inflammatory analgesic drugs: commonly used drugs are ibuprofen, diclofenac sodium, acetaminophen, aspirin, celecoxib and so on. It can play the role of anti-inflammatory and analgesic to relieve symptoms. Common adverse reactions are gastrointestinal irritation. 2. Tramadol hydrochloride: used for acute chronic moderate pain, adverse reactions, occasional sweating, nausea and vomiting, weakness, drowsiness and so on. Stone attacks need to go to the hospital in time for examination, the drug needs to be used under the guidance of a professional doctor.