Prolonged defecation with corkscrew can be harmful to the body. Keserol belongs to the lubricating laxative, is a colorless clarified viscous liquid containing glycerin, injected into the rectum can lubricate and stimulate the intestinal wall at the same time, soften the stool, and help to promote defecation; therefore, it can be used to improve the symptoms of constipation, but also for the prevention and treatment of chapped hands and feet. Although Kefir has a certain therapeutic effect on constipation, it is a hypertonic laxative, which may make the body dependent after long-term use, causing a decline in intestinal function, which in turn aggravates the symptoms of constipation; therefore, it is not recommended to defecate with Kefir for a long period of time. In addition, the use of Coca-Cola requires the insertion of the delivery container into the anus, so there is a risk of scratching or puncturing the skin around the anus or the rectal mucosa, and prolonged use of Coca-Cola may also lead to damage to the rectal mucosa. It should be noted that the drug is contraindicated in people who are allergic to Capsaicin, intestinal perforation, with nausea, vomiting, abdominal pain and bleeding hemorrhoids, etc.; after the use of the drug may be rectal irritation, anal discomfort, skin sensitization and other adverse reactions. Patients who need to be treated with Keflex should use the drug under the guidance of a doctor.