Cerebral cortex atrophy is mostly considered to be caused by ischemia and hypoxia of the brain due to impaired blood supply to the brain, which is mainly treated by improving blood circulation. Clinical application of danshen, safflower, panax ginseng, ginkgo biloba drip pills, peiyuan tongbao capsule, or intravenous infusion of shuxianning, shuxuetong, chuanxiongxiong zhen combined with cerebral lutong will slow down the progression of the patient’s condition. Patients in the advanced stage may suffer from memory loss, inattention, disordered thinking, which may also cause dementia in patients. Drugs to improve cerebral metabolism can be applied, and cytidine diphosphate choline, piracetam, and olanzapine are generally used in the clinic, and vincristine and cerebroside myosin can also be used. If the patient has severe cerebral cortical atrophy, the visual field may be decorticated.