Chromosome 7 deletion is a chromosome fragment deletion and may not necessarily be a disease. Chromosome deletions are generally faced with three major clinical conditions, namely mental retardation, overall developmental delay, and multiple malformations, in addition to the possibility of epilepsy, obesity, autism, and speech delays. The lack of chromosome segments may cause disease, however, it may not. Whether or not a partial chromosome deletion is pathogenic is generally related to the number and significance of the missing genes. At the same time, mechanisms such as invisible carryover, gene imprinting effects, and episodic insufficiency can contribute to the normal phenotype of an individual. In order to compensate for the fact that chromosomal deletions can lead to malformed fetuses, it is recommended that both husband and wife try to go to the hospital at the same time to receive eugenic screening, especially chromosomal testing, before preparing for pregnancy; it is also important to do a good job of pregnancy tests during pregnancy, especially screening for Down’s Syndrome and 4D ultrasound macro-analysis, etc., in order to avoid adverse consequences.