The sudden growth of many closed mouth acne (i.e. whitehead acne) is mostly related to endocrine and sebaceous gland keratinization abnormality and other factors. 1. Endocrine factors: If the level of androgen in the body is too much, it will lead to the sebaceous glands to secrete vigorously, which will lead to the sudden growth of many whiteheads on the face. 2. Sebaceous gland keratinization abnormality: Suddenly long a lot of whiteheads on the face of pimples may also be caused by sebaceous gland keratinization abnormality, sebaceous gland duct keratinization abnormality will cause hair follicle mouth narrowing, due to the local sebum can’t be discharged, it will form pimples. There are many reasons for the sudden growth of whiteheads on the face, it is recommended to pay attention to personal hygiene, keep the facial skin clean. If necessary, consult a doctor for examination, and cooperate with the doctor to standardize the treatment.