At 11:25 a.m. on March 21, 2014, a 43-year-old comatose woman was transferred to the intensive care unit of our hospital’s respiratory medicine department from out of town with a flushed face, shortness of breath, already in deep coma, and a lung CT showing large solid lesions in both lungs, with almost no normal lung fields visible. “Save my lover, she is only 40 years old, and there are two school children at home. ……” The patient’s family members’ eyes full of tears were filled with a thirsty gaze. The director of the respiratory department, Han Zhihai, quickly formed a rescue team and gave tracheal intubation, ventilator-assisted breathing and life support treatment. The patient had recurrent high fever, coughing rust-colored pus sputum, and large solid changes in both lungs within 1 month, and the disease progressed so rapidly that there was no doubt about severe pneumonia. Was it a virus or a bacterium? Fungus? In this case, the treatment team decided to give broad-spectrum coverage antibiotics first, while repeatedly performing bronchoscopy and collecting pathogenic specimens. After repeated communication with the laboratory doctor, the pathogenic organism was finally identified as a severe pulmonary Nocardia infection. Nocardia infection? The young physicians all showed a confused look. “Pulmonary syringomyelia, the disease is rare in the clinic, this should be the first case received by our hospital, clinically syringomyelia is caused by the genus Syringobacter, limited or disseminated, acute or chronic septic disease, astrocytic syringobacter mainly cause invasive disease, is a conditional pathogenic bacteria, present in the soil, bacterial dust, soil or food through the respiratory tract, the It enters the body through the respiratory, skin, or digestive tracts and is then confined to an organ or tissue or disseminated to the brain, kidneys, or other organs via the bloodstream. The disease has a high mortality rate …..” On March 22, the patient was promptly given Synthroid, an effective drug currently reported for the treatment of Nocardia infection, and on March 23, the condition did not improve as expected. The heavy financial pressure and no significant improvement in the condition of the family from the countryside to support, “she can be well? We still have two children, they are both in school, I have to think about my children in the future.” The man from the countryside bowed his head and spilled tears on his lapel. “She is still very young, give us a few more days, okay?” , the treatment team repeatedly communicated with and encouraged the patient’s family. And led everyone to inquire a lot of clinical data, analyze and summarize, and reformulated the combined treatment plan of Synthroid + Linezolid + Tylenol + Amikacin, and daily tracheoscopic aspiration, during that time, every doctor and nurse who passed by the bedside would take the initiative to aspirate for her, with careful care, and the effort did not fail, 4 days later, the condition turned around, the patient’s temperature peak moved down; on April 1, the patient’s temperature was normal On April 1, the patient’s temperature was normal, the sedative drugs were withdrawn, and the chest X-ray showed that the lung shadow was absorbed; on April 3, the patient was well conscious and her spontaneous breathing gradually returned to normal; on April 7, she was taken off the machine and extubated, and on April 10, her body temperature had returned to normal for many days, and she stood up again, and most of the lesions in both lungs were absorbed on the lung CT; on April 15, she could walk out of the ward by herself and gave the brightest smile to the medical staff who had worked with her for nearly one month. On April 15, she was able to walk out of the ward by herself and gave her brightest smile to the medical staff who had worked with her for nearly a month.