Warty gastritis is a common and specific type of gastritis with characteristic morphologic and pathologic changes, also known as chronic erosive gastritis, pockmarked gastritis, diffuse smallpox gastritis, or octopus sucker gastritis. The domestic reported endoscopy rate is 3.3%. Related studies have shown that warty gastritis is closely related to the occurrence of gastric cancer. 1, Japanese scholar Hirota examined 57 cases of early gastric cancer with warty gastritis among 1900 cases of gross specimens. 2, Yao Yirong et al. observed 82 cases of verrucous gastritis, and the basic pathological features of the first endoscopic lesion biopsy were: hyperplasia of the pyloric gland and small concave epithelium, and pseudopyloric gland hyperplasia. The follow-up ranged from 1-5 years, and cancer was found in 4 cases. 4.88%. The duration of carcinoma ranged from 1-3 years, with an average of 21 months, and all occurred at the primary lesion. The surgical pathology was all intra-mucosal adenocarcinoma. 3, Li Shi et al. found one case of adenocarcinoma in 191 cases of verrucous gastritis. It was a warty change, and there was a lesion area with atypical hyperplasia and cancer foci co-existing, and there was a transition between warty lesion and cancer foci, indicating that warty gastritis may be cancerous. 4, Zhu Minghua et al. performed immunohistochemical examination of monoclonal antibody MG7 in patients with warty gastritis occurring with the mucosa of the gastric sinus, and the positive rate was 12.5%. With intestinal hyperplasia and atypical hyperplasia, the positive rate was 13.3% – 29.4% . It is suggested that warty gastritis, especially with atypical hyperplasia, has a certain tendency to become cancerous. 5, Hp infection is the main cause of warty gastritis. It has been confirmed that Hp is the main initiating factor for the development of chronic gastritis into gastric cancer. The results of domestic and foreign research show that warty gastritis is a precancerous lesion of gastric cancer, the correlation between warty gastritis and gastric cancer and related genetic research is still in progress. There is a clinical need for prospective clinical observation of verrucous gastritis to prevent carcinoma.