Sacral nerve root cysts can be treated by medication and surgery. 1.Drug treatment (1) Analgesic and anti-inflammatory drugs: non-steroidal analgesic and anti-inflammatory drugs such as celecoxib and ibuprofen can be applied according to the doctor’s instruction. The common adverse effects are vomiting, malignant and other gastrointestinal symptoms, and prolonged application of these drugs may lead to gastrointestinal hemorrhage, so it is necessary to pay attention to the observation and consult the doctor in time. (2) Drugs for constipation: sacral nerve root cysts can cause constipation and other symptoms, after the symptoms of constipation, under the guidance of the doctor can be applied to promote gastrointestinal peristalsis, senna and other drugs to promote excretion. 2. Surgery: Partial excision of the cyst wall and nerve root cuff plasty can be performed. Under microscope and neurophysiological monitoring, part of the cyst wall can be excised and the remaining part of the wall can be folded and sutured, which can reduce or eliminate the cyst. In addition, interventional surgery can be performed with the assistance of CT imaging, and so on. When sacral nerve root cyst occurs, it is necessary to consult a doctor in a timely manner, and actively carry out appropriate treatment under the guidance of specialists, which can help improve the condition as soon as possible.