For patients with mild insomnia, both eszopiclone tablets and zopiclone can be used. For refractory insomnia, eszopiclone is more effective and zopiclone can not be replaced, but whether it can be replaced or not, it should be followed by doctor’s advice. 1. Eszopiclone belongs to the benzodiazepine class of drugs, the main role of sedation, treatment of insomnia, anti-anxiety, etc., for insomnia patients, especially refractory insomnia patients better than zopiclone. However, long-term use of eszopiclone tablets has a certain degree of addiction and dependence. 2. Compared with Eszopiclone, Zopiclone is a new type of drug for the treatment of insomnia, which generally does not have the effects of anti-anxiety, sedation, etc. The addiction and dependence are significantly lower than that of Eszopiclone, but it is not applicable to patients with refractory insomnia. Depending on the individual situation, you need to choose the most suitable drugs for your condition under the guidance of your doctor, do not blindly use drugs, so as not to cause adverse consequences.