Helicobacter pylori infection is not a big disease, but it should not be taken lightly. If the disease progresses, it may lead to chronic gastritis, gastric ulcer, or even evolve into stomach cancer. H. pylori infection is a relatively common disease, mainly manifested as acid reflux, heartburn, bad breath and stomach pain. Long-term H. pylori infection may lead to the development of chronic gastritis, gastric ulcer, and even gradually evolve into stomach cancer. More than 70% of patients with H. pylori infection do not have any clinical symptoms, 10% to 20% may develop peptic ulcers, about 10% of patients may develop functional dyspepsia, and about less than 1% may cause gastric cancer. If good hygiene habits can be maintained, the reinfection rate after H. pylori eradication is not high. H. pylori usually requires quadruple therapy for intervention, such as amoxicillin, metronidazole, omeprazole and colloidal bismuth pectin. The specific medication needs to be combined with the actual situation of the patient, and it is recommended that the patient use the medication under the guidance of the doctor, so as not to delay the time of treatment.