Taking antibiotics before a mycoplasma test is not recommended and may affect the results. Mycoplasma test is to check for the presence of mycoplasma infection in the specimen being tested, and taking antibiotics will remove some of the mycoplasma, resulting in undetectable mycoplasma in the specimen, which may affect the test results. Therefore, if a mycoplasma test is needed, antibiotics should be avoided before the test. Common sites of infection for Mycoplasma include the respiratory and urinary tracts, which can cause coughing, sputum, frequent urination, and urinary urgency. Mycoplasma is treated mainly with antibiotics, and commonly used antibiotics include azithromycin, doxycycline, and levofloxacin. Treatment for mycoplasma usually takes 1 to 2 weeks and the full course should be completed for cure.