Whenever you eat durian, you will have an upset stomach. The main considerations are allergy, deterioration of durian, and the presence of digestive diseases in the patient. 1. Allergy: when the patient is allergic to durian, there will also be nausea, vomiting, diarrhea, bloating, indigestion and other discomforts such as upset stomach once eating durian. 2. Durian deterioration: when durian is not fresh or when durian has been stored for too long and durian has deteriorated, at this time, gastroenteritis will be caused after eating durian, resulting in stomach acidity, stomach pain, nausea, vomiting and other stomach discomforts. 3. Digestive system diseases: when the patient has gastritis, gastric ulcer and other digestive system diseases, durian stimulation at this time will also trigger the onset of digestive system diseases, stomach discomfort. In addition, eating durian stomach upset, there may be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.