High urine squamous epithelial cells may be caused by vaginal secretion contamination, and may also be caused by chronic pyelonephritis or chronic bladder mucosal lesions. 1. Vaginal secretion pollution caused by: under normal circumstances in the urine only a small number of squamous epithelial cells, women due to the special physiological structure, the vagina and the urethra is very close to the vaginal secretion is also very easy to mix into the urine. When the squamous epithelial cells in the urine are high, it may be contaminated by vaginal secretions. 2. Chronic pyelonephritis: This disease is mostly related to the complexity of the urinary tract, which will cause symptoms of frequent urination and urgency, and will be accompanied by fever, fatigue and anorexia. Chronic pyelonephritis leads to shedding of squamous epithelial cells and increases the level of squamous epithelial cells in the urine. 3. Chronic bladder mucosal lesions: Chronic bladder mucosal lesions are urological diseases that cause inflammation and distension of the bladder, leading to accelerated shedding of squamous epithelial cells, resulting in high urine squamous epithelial cells. High urine squamous epithelial cells can also be caused by other factors. In conclusion, if you have high urine squamous epithelial cells, you must go to the regular hospital to find out the specific cause and find the appropriate treatment plan, in order to get well soon.