Colon cancer T3N0M0 is defined as colon cancer foci penetrating the intrinsic muscular layer to the subplasma membrane without lymph node and distant metastasis, and belongs to stage IIA. Colon cancer is a malignant tumor originating from the epithelial cells of the colon and is a common gastrointestinal cancer, and its development is related to adenomatous polyps, obesity, smoking, excessive fat intake and other factors. According to the TNM staging method of International Union Against Cancer, colon cancer can be divided into stages I-IV. T refers to the primary lesion, T3 is the cancer foci penetrating into the intrinsic muscle layer to the subperitoneum or invading the surrounding tissues without peritoneal coverage; N refers to lymph node metastasis, and N0 is the case of no lymph node metastasis; M is the case of distant metastasis, and M0 is the case of no distant metastasis. T3N0M0 is stage IIA, which is an early stage of colon cancer, and the 5-year survival rate can be up to 70% after radical surgery, radiotherapy, chemotherapy and other comprehensive treatments. It is recommended that patients should go to regular hospitals as early as possible once they are detected, give standardized treatment under the evaluation and guidance of professional doctors, and follow the doctor’s instructions for regular review to monitor the changes of their conditions.