If the patient has high blood pressure, a sudden decrease in blood pressure can cause adverse consequences. Hypertensive patients who have a sudden drop in blood pressure will experience ischemia-reperfusion injury to the aorta, cerebral arteries, coronary arteries, and cardiovascular, etc. In severe cases, peripheral circulation, impaired capillary internal circulation, and microcirculatory dysfunction can occur. The adverse consequences of the dysfunction are difficult to recover, especially causing damage to the corresponding target organ tissues, such as cerebral ischemia and hypoxia, cardiomyocyte ischemia and hypoxia, and renal ischemia-reperfusion disorders. Patients may experience different degrees of clinical manifestations, such as dizziness, headache, nausea and vomiting due to cerebral ischemia and hypoxia. Myocardial ischemia causes chest tightness, shortness of breath, palpitations, discomfort in the precordial region or even a crushing sensation. Kidney ischemia can cause symptoms such as oliguria or even urinary closure. In severe cases, sudden cerebrovascular disease can occur, such as sudden cerebral infarction, cerebral embolism, acute myocardial ischemia, and acute renal insufficiency. These conditions are the adverse consequences of the sudden drop of blood pressure in hypertensive patients resulting in insufficient blood supply to capillaries and insufficient blood supply to large arteries.