Hypertensive patients have a wide range of antihypertensive drugs, including calcium antagonists, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, diuretics, beta-blockers and so on. Hypertensive patients should pay attention to drug therapy: 1, choose a long duration of action (long-acting agents), less side effects of drugs is preferred. There are many patients who need 2 or more drugs in combination. At present, there are many compound antihypertensive preparations on the market, generally not as the first choice, such as the choice should be used under the guidance of cardiovascular doctors. 2. Advise patients to adhere to treatment and improve their compliance with treatment is the key to successful treatment. Lifestyle changes as a basic treatment must be carried out throughout, such as control of diet, exercise, smoking and alcohol cessation and maintaining psychological balance. The majority of patients need to take medication for a long time or for life. 3. Strive to achieve the “standard” of patient treatment. The ultimate goal is to reduce strokes, myocardial infarction and kidney damage, and to minimize mortality. Blood pressure should be more strictly controlled in patients with diabetes and chronic kidney disease.