Toenails fall off toes red and swollen and itchy, consider trauma-induced infection, onychomycosis, eczema involving the nails, etc., mainly medication, surgical treatment, according to the specific causes of the selection of appropriate drugs. 1. Trauma-induced infection: toenails can fall off if they are bumped or smashed, and if you don’t pay attention to hygiene, it can cause infection and redness, swelling and itching, you can apply antibiotic ointment, such as erythromycin ointment and fusidic acid cream to control the infection. 2. Ringworm of the nail: ringworm of the nail is a kind of fungal infection, when it is more serious, it can also lead to nail loss, and accompanied by redness, swelling and itching, you can take terbinafine, itraconazole, fluconazole and so on, you can also cooperate with the laser treatment, photodynamic therapy and so on. 3. Eczema involving nails: If foot eczema involves the nails will also lead to nail loss, and accompanied by redness and itching symptoms, mainly applying glucocorticoid drugs, such as dexamethasone cream, hassinide cream. Toenail off the toes red and itchy, to seek medical attention in a timely manner to clarify the cause of the disease, and for the cause of the standardized treatment, the above drugs should be used in accordance with the doctor’s instructions, can not be blindly used by themselves.