Sinus arrhythmias, in general, are not significantly harmful. Sinus arrhythmia often occurs in a physiological state, so the general treatment is to improve the lifestyle and avoid strain and staying up late, while for pathological conditions sinus arrhythmia often occurs on top of organic heart disease. Sinus arrhythmia may increase the burden on the heart, but treatment of the primary cause is the main concern. For pathological sinus arrhythmia, on the basis of treating the primary pathology, beta-blockers such as metoprolol tartrate tablets and bisoprolol fumarate tablets can be used for symptomatic management, as well as proprietary Chinese medicines such as heart stabilizing granules and sengsong nourishing heart capsules. The application of myocardium-nourishing related drugs, such as trimetazidine hydrochloride tablets and coenzyme Q10 capsules, can be given.