The differences between lymphoma and lipoma are mainly in the following 3 points: 1. In terms of the nature of the disease, lymphoma is a malignant tumor of the blood system, while lipoma is the most common benign tumor on the body surface. 2. In terms of the treatment of the disease, most lymphomas require chemotherapy or even radiotherapy, while lipoma is a benign tumor that can be cured by surgical excision under local anesthesia. 3. In terms of the prognosis of the disease, because Lymphoma is a malignant tumor, and even chemotherapy and radiotherapy have the risk of tumor metastasis and recurrence, while lipoma is a benign tumor, and can be cured by complete removal of lipoma through local anesthesia.