Novel coronavirus pneumonia is characterized by fever, dry cough, and malaise, and some patients may have nasal congestion, runny nose, and sore throat, while some patients may also have no obvious clinical symptoms. Severe patients tend to develop respiratory distress or hypoxemia one week after the onset of illness. Mildly ill patients may present with low-grade fever, malaise, smell and taste impairment, etc., without pneumonia. In severe cases, dyspnea and/or hypoxemia, septic shock, acute respiratory distress syndrome, uncorrectable metabolic acidosis, hemorrhagic coagulopathy, and multiorgan failure occur one week after the onset of symptoms. Symptoms in children are relatively mild, and some children and neonates have atypical symptoms, such as vomiting, diarrhea, poor response and shortness of breath. Most patients have a good prognosis, but a few are in critical condition, mostly in people with chronic underlying diseases, the elderly, late pregnancy and perinatal women, and obese people. When fever, dry cough, fatigue and other possible symptoms of new coronavirus infection, we need to pay attention immediately, go to a designated hospital for timely consultation, if necessary, need to carry out nucleic acid testing, chest X-ray, CT and other further examination to confirm the diagnosis, to avoid delaying the condition. Tips] The “new coronary pneumonia, new coronary virus pneumonia” mentioned in this article has been renamed to “new coronary virus infection” on December 26, 2022 by the National Health Commission.