It is difficult for women to sleep at night with soreness in the calves, considering that it is related to muscle strain, lumbar spine disease, vascular disease and other causes. According to the cause of the disease, general treatment, physical therapy, drugs, surgery and other methods of treatment. 1. Muscle strain: If you walk too much or exercise too much, it will cause calf muscle strain, while lactic acid secretion increases, and cause calf soreness. This can be treated by hot compresses, massages, etc. With the absorption and metabolism of lactic acid, the soreness can be quickly recovered. 2. Lumbar spine disease: such as lumbar disc herniation, such as for the nerve root caused by compression, can also cause calf swelling. Usually pay attention to rest, can be applied to nutritional nerve drugs, such as methylcobalamin and other treatments. If the condition is more serious, causing serious impact on life, surgical treatment, such as minimally invasive intervertebral foramenoscopy surgery. 3. Vascular diseases: such as varicose veins, varicose veins will cause blood stagnation, affecting the blood circulation in the legs, which will also cause calf soreness. Patients usually avoid standing for a long time, avoid heavy labor, and can wear compression stockings to improve circulation. Vasoactive drugs, such as sodium hepaticoside, can be applied to treat the condition. If the symptoms are serious, surgery can be performed, such as high saphenous vein ligation. When the calf soreness is difficult to sleep, you can go to the hospital to further identify the cause of the disease, and then targeted treatment. The above drugs need to be applied under the guidance of a physician.