Sixteen months baby recurrent fever 39.4 ℃ can be seen in respiratory diseases, urinary tract diseases, etc., need to be treated according to the cause, such as the consideration of influenza, the need to use oseltamivir phosphate treatment, the course of the disease reasonable antipyretic and so on. 1. Respiratory diseases: such as influenza caused by influenza virus infection in children, there may be recurrent fever, body temperature presents high fever, may appear 39.4 ℃, often accompanied by fatigue, depression and other general symptoms, may have epidemiological contact history. For such babies need to use oseltamivir phosphate antiviral treatment, the course of the disease for the temperature exceeds 38.5 ℃ need to be reasonable use of antipyretic drugs (such as ibuprofen) symptomatic antipyretic. 2. Urinary tract diseases: such as urinary tract infections, may appear above symptoms, with or without urinary frequency, urinary urgency or urinary pain and other symptoms, improve the urine routine examination can assist in the diagnosis. For treatment, it is necessary to drink more water, use antibacterial drugs (such as cefaclor) anti-infective treatment and reasonable fever reduction. 3. Hematologic diseases: such as hemophagocytic lymphoid hyperplasia, there may be recurrent fever, mostly irregular fever, high temperature, may be accompanied by anemia and hemorrhagic symptoms. These children need to be treated with drugs such as dexamethasone and methotrexate for chemotherapy or hematopoietic stem cell transplantation. 4. Others: Kawasaki disease may also occur, and may be accompanied by skin rashes, swollen lymph nodes or conjunctival congestion. Treatment requires the use of gammaglobulin and aspirin, etc. for treatment. Sixteen-month-old babies with recurrent fevers of 39 degrees 4 need to be actively consulted, evaluated and treated by a specialist.