Gastroesophageal reflux with bitter mouth belongs to the categories of “acid vomiting” (vomiting acid water) and “noisy (feeling like hunger, emptiness with burning in the stomach)” in Chinese medicine. According to the identification of Chinese medicine, prescription medicines such as Chai Hu Shuo Liver Essence and Zuo Jin Pill can be used for treatment. 1. Chai Hu Shuo Liver Essence is composed of Chen Pi, Chai Hu and Chuan Xiong, etc. It has the efficacy of dredging the liver and regulating the stagnation of liver qi (regulating the stagnation of liver qi), invigorating blood circulation and relieving pain (relieving pain by removing blood stasis), etc. It is also effective in relieving pain by removing blood stasis. It is used for treating liver-qi stagnation (stagnation of liver qi) syndrome, which is characterized by pain in hypochondrium and ribs, depression, irritability, belching (hiccup), and distension of epigastrium and abdomen. The adverse reactions and contraindications of this formula are not clear, clinically should not be taken for a long time, allergies and hypersensitivity to this formula is prohibited. 2. Zuo Jin Wan is composed of Rhizoma Coptidis and Cornu Cervi Pantotrichum, which has the efficacy of diarrhea of fire (clearing away the evil of fire), detoxification of the liver (regulating the liver qi), harmonization of the stomach (regulating the stomach and internal organs), and relief of pain. This formula is used for treating liver fire in the stomach (exuberant fire and heat in the liver invading the stomach and internal organs), with symptoms such as pain in the epigastrium and coats of the stomach, bitter taste in the mouth, noisiness, and vomiting of sour water. The adverse reactions and contraindications of this formula are not clear, the diet should be light, avoid alcohol and spicy, cold, greasy food, it is advisable to maintain a relaxed mood. If symptoms occur, it is recommended to seek medical advice in a timely manner, under the guidance of a doctor to identify the evidence of the use of medication, do not self-medication, in order to avoid adverse reactions, endangering health.