Low neutrophil count may be caused by drug factors, hematopoietic abnormalities, infections, immune factors and so on. It is recommended to consult a doctor in time to determine the cause of the disease and then treat it under the doctor’s guidance. 1. Drug factors: clinically, the main drugs that cause low neutrophil count are aspirin, indomethacin, ibuprofen, isoniazid, rifampicin, phenytoin sodium, rifampicin, azathioprine, levamisole, acetazolamide, etc. After stopping taking the corresponding drugs, the neutrophil count can be lowered. After stopping the corresponding drugs, the number of neutrophils will gradually return to normal. 2. Abnormal hematopoietic function: usually due to vitamin B₁₂ deficiency, folic acid deficiency, metabolic disorders, aplastic anemia, acute leukemia, myelodysplastic syndromes and other diseases caused by abnormal hematopoietic function, we need to consult hematology in time, and carry out treatments after the cause is clear. For example, acute myeloid leukemia should be treated with chemotherapy such as cytarabine and erythromycin. 3. Infection: usually due to influenza virus, hepatitis virus, HIV infection, the phenomenon of neutropenia, children are more common. It is recommended to consult the doctor in time and give anti-infection treatment under the doctor’s guidance. Drugs include levofloxacin, etc. 4. Immune factors: Usually due to immune diseases such as systemic lupus erythematosus and rheumatoid arthritis, the number of neutrophils is low. After the disease is cured, the number of neutrophils will gradually return to normal. Medications include prednisone. Specific diagnosis and treatment should be carried out under the guidance of a physician.