Two major misconceptions about blood transfusions?

  The Ministry of Health requires that the proportion of autologous blood transfusion in tertiary general hospitals should reach 20%. However, the current proportion of autologous blood transfusion in China is very low, accounting for only about 1%. In many countries in Europe and the United States, autologous blood transfusions are commonly carried out, accounting for 20% to 40% of all blood used, and more than 60% in the United States and Australia. In Japan, more than 80% of elective surgery patients will prepare 2 to 3 units of autologous blood before surgery and transfuse themselves during surgery.  Myth 1: Transfusion of other people’s plasma can “make up” for itself Plasma can provide a variety of plasma proteins, including antibodies and clotting factors, so it does have a role in raising plasma protein levels, increasing colloid osmotic pressure to maintain blood volume, enhancing the patient’s resistance to infection and repair, and correcting bleeding caused by clotting disorders. However, its role as a general nutritional support is limited and it cannot be used as a “nutritional product”.  Moreover, plasma is blood with red blood cells removed, so there is still a chance of contracting diseases from the transfusion, and its transfusion reaction is no less than that of other blood transfusions. Therefore, it should not be used as a “panacea” and should not be transfused if it can be done, and should be done in small amounts if it can be done sparingly.  Myth 2: Whole blood is more “complementary” than component blood. Under the existing maintenance conditions, platelets lose most of their activity after 12 hours; white blood cells lose their function after 8 hours; the content of coagulation factor VIII decreases to 10-20% of normal after 48 hours, so only red blood cells have function in the maintenance fluid after 48 hours, and the rest of the active components have mostly lost their function. The rest of the active ingredients have mostly lost their functions.  Moreover, for the elderly, infants and children, and those with cardiac insufficiency, too much whole blood transfusion will easily cause circulatory overload.  Secondly, the amount of leukocytes, platelets and coagulation factors in whole blood is very small, which has almost no therapeutic effect and may cause the recipient to produce the corresponding antibodies, causing fever and allergy.  The advantages of component transfusion: 1. It is safer to avoid adverse reactions caused by the input of unwanted components.  2.Great purity, high concentration, and good therapeutic effect.  3.Saving blood source and increasing the efficiency of using whole blood.