Pain in the arm after HPV vaccination is related to the vaccine stimulating the muscles and vascular nerves at the injection site and is a normal reaction to the vaccine. HPV vaccine, also known as cervical cancer vaccine, includes not only treated human papilloma virus, but also other added ingredients, such as immune adjuvant to enhance immunity and bacteriostatic agent to prevent the reproduction of other pathogenic microorganisms. After these ingredients enter the human body, they may cause some irritation to the tissue at the injection site, thus causing local pain, which will be relieved in about 3-5 days. If there is redness, swelling, fever or rash at the injection site at the same time, prompt medical consultation is required.