There are many reasons for gallstones with bitter mouth, which can be caused by dietary disorders and other life factors, or it can be a symptom of certain diseases, such as bile reflux gastritis, cholecystitis, and so on. 1. Dietary disorders: If the patient often eats spicy or greasy food, resulting in weakened digestive function, food stagnation in the stomach is not easy to digest, gallstones symptoms worsened, it can cause bitter mouth. 2. Bile reflux gastritis: it is the gastric mucous membrane damage caused by bile reflux from the duodenum into the stomach, which can be caused by gallstones, diabetes and other factors. The main symptoms may be manifested as abdominal pain, abdominal distension, nausea and vomiting, or may be accompanied by bitter mouth. 3. Cholecystitis: It is an inflammatory disease of the gallbladder, which can be caused by gallbladder stones and bacterial infection. The main symptoms may be severe colic in the right upper abdomen, nausea and vomiting. There are other reasons for gallstones with bitter mouth, such as bile duct obstruction caused by gallstones, etc. You should go to the hospital immediately for relevant examinations to clarify the cause of the disease and actively cooperate with the doctor’s treatment.