Aortic and coronary artery calcification is usually treated with lipid-regulating and antiplatelet medications and a healthy lifestyle. Calcification of the aorta and coronary arteries usually occurs when the walls of the blood vessels are damaged after aging and when the elasticity of the blood vessels is changed, and it is common in the elderly, patients with high blood pressure, and patients with atherosclerosis. CTA examination of the coronary arteries can determine the extent of calcification and the degree of narrowing of the vessels, which can be treated with medications or interventional procedures. Drugs are often used to lower blood lipids, such as atorvastatin, and antiplatelet drugs, such as aspirin and clopidogrel. When calcification is severe enough to cause severe narrowing of the blood vessel, stent implantation or interventional thrombolysis should be considered. Drugs need to be used under the guidance of a doctor, and patients should also pay attention to maintaining a healthy lifestyle in their daily lives. Low-salt and low-fat diet, appropriate exercise, quit smoking and drinking.