Peeling toes may be due to tinea pedis, herpes sweat, exfoliative keratolysis and other diseases, need to clarify the cause of the disease and then choose the appropriate drug treatment. 1. Tinea pedis: caused by fungal infections, can manifest as blisters, peeling, itching and other symptoms. Need to carry out antifungal treatment, such as external ketoconazole, econazole and other drugs, if necessary, can also take oral terbinafine, itraconazole and other antifungal drugs. The treatment cycle of tinea pedis is long, and it must be standardized to carry out a full course of treatment to avoid recurrence. 2. Sweat herpes: it is an eczema-like reaction, manifested as small blisters deep in the skin, peeling, itching, and other symptoms, often recurring. You can use tretinoin urea ointment, tacrolimus ointment, glycerite lotion and other medications to apply locally for drying, anti-inflammatory and antipruritic treatments, and take oral loratadine and other medications if necessary. 3. Exfoliative Keratolysis: manifested as blisterless peeling, often accompanied by sweating insufficiency, mostly in the change of season. This disease can be self-healing, if not accompanied by obvious symptoms of discomfort, generally do not need treatment; if the condition is serious, such as cracked skin, pain, you can use salicylic acid ointment, vitamin E cream, urea cream, and other medications applied locally. Peeling toes may also be caused by other factors, it is recommended that patients seek medical attention in a timely manner, in order to clarify the cause of the symptomatic treatment, to avoid self-medication, so as not to delay the condition. Avoid tearing the peeling skin in daily life, let it fall off naturally, so as not to cause infection.