The two white spots on the edge of the glans may be caused by diseases such as glans circumcision or pearly penile papules, as well as condyloma acuminatum. 1. glans penis: glans penis is urology more common disease, the cause is more complex, including bacteria and candida infection, etc., and may be too long foreskin, foreskin scale stimulation, etc., the main symptoms of local redness, swelling, pain, may also appear white dots. 2. pearly penile papules: pearly penile papules is the main manifestation of the glans coronal groove edge of the presence of small pimples, usually white or reddish, not fusion, usually no self-conscious symptoms. 3. acromegaly: acromegaly is mainly caused by human papilloma virus infection, in sexually active people more common, in the patient’s glans, foreskin or coronary groove and other parts of the papilla and cauliflower kind of small warts, with the development of the disease, warts will gradually increase in size, the surface of the vesicle ooze and other changes.